Poodle with Stranguria & Pollakiuria

A 7-year old spayed female miniature poodle was evaluated for stranguria and pollakiuria.  Three months prior to evaluation the dog had a routine cystotomy for cystic calculi, which were later confirmed to be calcium oxalate.  The patient developed signs of dysuria and stranguria approximately one month after surgery.  Radiographs confirmed no recurrence of cystic calculi, abdominal ultrasound did not reveal the reason for her clinical signs, and multiple urine cultures were negative.  Urinary antigen testing for transitional cell carcinoma was positive.

What is the sensitivity and specificity of urine antigen testing for transitional cell carcinoma?

Retrograde contrast cystourethrogram was performed, and the following image was obtained upon completion of the infusion of an iodinated contrast agent.

Describe the radiographic findings?  What are the differentials for these changes?

Rigid cystoscopy with a 1.9 mm cystoscopy was performed and the following video was obtained?
http://www.youtube.com/watch?v=qUWjQyB9pd8

Histopathology revealed mucosal inflammation but no submucosa was within the biopsy sample.   Based on the contrast cystourethrogram, cystoscopy, and biopsy results, what are the management options for this patient?

Category: Cases, Endoscopy, Genitourinary